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Proposal Number: 6695

Domain: Healthcare

Theme(s): Maternal and child health
Point of care diagnostic tests and surveillance systems for common non-communicable and Infectious diseases

Supporting Central Government Agency: Ministry of Health and Family Welfare

Budget (Rs. Lakhs): 122.16

Principal Investigator: Dr. J.P. Singh

Principal Investigator Institute: Indian Institute of Technology Delhi

Prof. Prashant Mishra ,Indian Institute of Technology Delhi
Dr. Neena Valecha ,National Institute of Malaria Research
Dr. Deepali Savargaonkar ,National Institute of Malaria Research

Domain: Healthcare

Project Title

Development of SERS based ultra-sensitive, rapid, portable and field deployable platform for detection of pathogenic bacteria and Dengue virus

Project Images

Image Caption:Hand-held SERS platform using silver nanorods arrays for rapid and on-site detection of pathogenic bacteria and Dengue virus.

Web Abstract

A new handheld, field-deployable SERS based diagnostic tool having capabilities of rapid on-chip specimen separation and detection of Dengue virus and pathogenic bacteria like Staphylococcus aureus and Escherichia coli for point-of-care diagnostics will be developed. The current available methods for identification of bacteria/virus such as biochemical test, PCR are time consuming and laborious. Our novel Ag nanorod based surface enhanced Raman scattering substrates fabricated by e-beam glancing angle deposition (GLAD) system will provide rapid and accurate detection of pathogenic bacteria and dengue virus. The hypothesis is that SERS spectrum provides a unique “molecular fingerprint” of individual virus/bacteria based on their specific molecules that are in contact with metal nanoparticles without any species-specific reagents typically required for virus/bacteria signal amplification.

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