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Proposal Number: 7075

Domain: Healthcare

Theme(s): Point of care diagnostic tests and surveillance systems for common non-communicable and Infectious diseases

Supporting Central Government Agency: Ministry of Health and Family Welfare

Budget (Rs. Lakhs): 149.97

Principal Investigator: Prof Rinti Banerjee

Principal Investigator Institute: Indian Institute of Technology Bombay

Co-Investigators:
Dr Gita Nataraj ,GS Medical College and KEM Hospital, Mumbai
Dr B R Das ,SRL Diagnostics Ltd
Dr Rishi Adhikary ,Indian Institute of Technology Bombay
Dr Biji Balakrishnan ,Indian Institute of Technology Bombay
Dr. Sucheta P. Dandekar ,Seth G. S. Medical College and KEM Hospital

Domain: Healthcare

Project Title

Instrument-free Point-of-care Device for Detection of Pathogens and Antimicrobial resistance

Project Images

Image Caption:Concentration of Bacteria on a Nanoparticle impregnated Smart Substrate for Detection of Pathogens and Antimicrobial resistance in various Infections

Web Abstract

Multidrug resistance in bacterial infections is increasing globally. The essential first step of rational antibiotic use is the diagnosis of whether the infection is of bacterial or viral origin and then identification of the bacteria. The existing methods for the distinguishing bacteria from viruses involve the use of expertise in microscopy, serology and microbiological culture. We will develop and validate a point of care device for distinguishing bacteria from viruses, and the further classification and identification of bacteria into Gram positive or negative and a preliminary antimicrobial sensitivity to common drugs. This platform will help in screening causative organisms in infections and will be inexpensive, accessible, affordable, and easy to read. This will enable triage of those cases that require antibiotic therapy and those that require further referrals. Such a system will decrease the indiscriminate use of antibiotics and address the emergence of antimicrobial resistant strains globally.