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Proposal Number: 4404

Domain: Healthcare

Theme(s): Point of care diagnostic tests and surveillance systems for common non-communicable and Infectious diseases

Supporting Central Government Agency: Ministry of Health and Family Welfare

Budget (Rs. Lakhs): 230.40

Principal Investigator: Professor Rohit Srivastava

Principal Investigator Institute: Department of Biosciences & Bioengineering, Indian Institute of Technology Bombay, Mumbai

Co-Investigators:
Dr. Vinay Saini ,Department of Biosciences & Bioengineering, Indian Institute of Technology Bombay, Mumbai
Prof M. Singh ,Lionex Diagnostics and Therapeutics, Germany, Tel: 0049 531 2601266 (Web: www.lionex.de)
Dr. Joan Miquel Balada Llasat ,Associate Director, Clinical Microbiology & Assistant Professor, Clinical Pathology, Division 1492 E Broad St, Columbus, OH,43205 Office: 614 257-2785
Dr. Dhanji P Rajani ,in-charge of Microcare Laboratory and Tuberculosis Research Centre (RNTCP), Surat, Gujarat
Dr. U D Gupta ,Director-in-charge & Scientist-F), National Jalma Institute of Leprosy and other Mycobacterial Diseases Phone: 91-0562-2331756,2232222
Dr. Lalit Anande ,CMO at Sewri TB Hospital, Mumbai

Domain: Healthcare

Project Title

Development, Evaluation & Scale-UP of non-invasive & low cost rapid TB diagnostics.

Web Abstract

Development, Evaluation & Scale-UP of Non invasive & Low cost Rapid TB diagnostics.

Around 10.4 million people FELL ILL FROM TB (WHO: 2016) (28,500 people per day). 1.8 million people died from TB including 400,000 with HIV + TB (over 4,900 people every day). 480 000 people have MDR TB in the world (2014).  Diagnosis of human TB is extremely difficult, time-consuming and in-efficient. No efficient, cost effective tests are available for an early diagnosis of these infections. Therefore, rapid, economical, and improved TB diagnostic tests are urgently needed. Our proposed tests (TB rapid serology tests, detection of LAM antigen in urine, MPT64 in sputum and EIOSPOT test) are rapid (20-25 minutes compared to 8 to 12 weeks for routine culture), low cost/affordable (compared to $10 for Xpert), do not require large equipment, mostly are point of care easy to use tests and only small amount of sample is needed.