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Proposal Number: 6060

Domain: Healthcare

Theme(s): Electronic decision support systems for primary care providers/ front line workers
Home based or Self Care
Point of care diagnostic tests and surveillance systems for common non-communicable and Infectious diseases

Supporting Central Government Agency: Indian Council of Medical Research

Budget (Rs. Lakhs): 73.20

Principal Investigator: Dr. Shubhajit Roy Chowdhury

Principal Investigator Institute: Indian Institute of Technology Mandi

Co-Investigators:
Dr. Prosenjit Mondal ,Indian Institute of Technology Mandi
Dr. Chander Singh ,Indian Institute of Technology Mandi
Dr. Subrata Ghosh ,Indian Institute of Technology Mandi

Domain: Healthcare

Project Title

A microfluidic based point of care testing device for measuring urine albumin using a novel organic dye

Project Images

Image Caption:Microfluidic Immunoassay Device with PC interfacing

Web Abstract

Albumin is the most abundant protein in the circularity system and plays a vital role in biological systems (maintenance of oncotic pressure and acid-base equilibrium, transportation of fatty acids).  Because of its cruciality, monitoring of albumin level in different bio-fluids becomes an advanced strategy for detecting different diseases in their commencement steps.Though urine dip-stick model is very common in market to detect albumin in urine but the high detection limit, interference of the color of bio-fluid and other significant factors restricted it from analyzing microalbuminuria and other nephritic disorders in their early stages. Therefore, a suitable long emissive Near Infra-Red (NIR)fluorescent turn–on dye based microfluidic point of care testing system for precise quantification of albumin in urine would help in detecting many health disorders in premature phase. This strategy will overcome the pitfall of present day albumin detection methods as well as accelerate the detection process at relatively lower costs.